Results OAEI 2020::Disease and Phenotype Track

Contact

If you have any question/suggestion related to the results of this track or if you notice any kind of error (wrong numbers, incorrect information on a matching system, etc.), feel free to write an email to ernesto [.] jimenez [.] ruiz [at] gmail [.] com or ianharrowconsulting [at] gmail [dot] com

Evaluation setting

We have run the evaluation in a Ubuntu 18 Laptop with an Intel Core i5-6300HQ CPU @ 2.30GHz × 4 and allocating 15Gb of RAM.

Systems have been evaluated according to the following criteria:

Precision and Recall with respect to a voted reference alignment or consensus alignment that has been automatically built by merging/voting the outputs of the participating systems in 2016-2020. We have used vote=3.

We have used the OWL 2 EL reasoner ELK to compute an approximate number of unsatisfiable classes.

Check out the supporting scripts to reproduce the evaluation: https://github.com/ernestojimenezruiz/oaei-evaluation

Participation and success

In the OAEI 2020 phenotype track 7 participating OAEI 2020 systems have been able to complete at least one of the tasks with a 8 hours timeout (see Table 1). DESKMatcher finished with an "OutOfMemoryException" in both tasks.

**Table 1:** System runtimes (s) and task completion.
System	HP-MP	DOID-ORDO	Average	# Tasks
LogMapLt	7	8	8	2
ATBox	16	21	19	2
LogMap	32	25	29	2
AML	102	200	151	2
Wiktionary	854	858	856	2
LogMapBio	1,355	2,034	1,695	2
ALOD2Vec	2,384	2,809	2,597	2
# Systems	7	7	765	14

Use of background knowledge

LogMapBio uses BioPortal as mediating ontology provider, that is, it retrieves from BioPortal the most suitable top-10 ontologies for the matching task.

LogMap uses normalisations and spelling variants from the general (biomedical) purpose SPECIALIST Lexicon.

AML has three sources of background knowledge which can be used as mediators between the input ontologies: the Uber Anatomy Ontology (Uberon), the Human Disease Ontology (DOID) and the Medical Subject Headings (MeSH).

Results against the consensus alignments with vote 3

Tables 2 and 3 show the results achieved by each of the participating systems against the consensus alignment with vote=3. Note that systems participating with different variants only contributed once in the voting, that is, the voting was done by family of systems/variants rather than by individual systems.

Since the consensus alignments only allow us to assess how systems perform in comparison with one another the proposed ranking is only a reference. Note that, on one hand, some of the mappings in the consensus alignment may be erroneous (false positives), as all it takes for that is that 3 systems agree on part of the erroneous mappings they find. On the other hand, the consensus alignments are not complete, as there will likely be correct mappings that no system is able to find, and there are a number of mappings found by only one system (and therefore not in the consensus alignments) which may be correct.

Nevertheless, the results with respect to the consensus alignments do provide some insights into the performance of the systems. For example, LogMap is the system that provides the closest set of mappings to the consensus with vote=3 (not necessarily the best system), while AML outputs a large set of unique mappings, that is, mappings that are not proposed by any other system. LogMap has a small set of unique mappings as most of its mappings are also suggested by its variant LogMapBio and viceversa.

HP-MP task

**Table 2:** Results for the HP-MP.
System	Time (s)	# Mappings	# Unique	Scores			Incoherence Analysis
System	Time (s)	# Mappings	# Unique	Precision	Recall	F-measure	Unsat.	Degree
LogMap	1,355	2,128	9	0.903	0.768	0.830	≥0	≥0%
LogMapBio	1,355	2,198	62	0.884	0.777	0.827	≥0	≥0%
AML	102	2,029	358	0.910	0.739	0.816	≥0	≥0%
LogMapLt	7	1,370	0	0.997	0.546	0.706	≥0	≥0%
ATBox	16	759	10	0.982	0.298	0.457	≥0	≥0%
ALOD2Vec	2,384	67,943	469	0.024	0.641	0.046	≥0	≥0%
Wiktionary	854	67,455	4	0.023	0.625	0.044	≥0	≥0%

DOID-ORDO task

**Table 3:** Results for the DOID-ORDO task.
System	Time (s)	# Mappings	# Unique	Scores			Incoherence Analysis
System	Time (s)	# Mappings	# Unique	Precision	Recall	F-measure	Unsat.	Degree
LogMapBio	2,034	2,584	147	0.945	0.625	0.752	≥0	≥0%
AML	200	4,781	195	0.682	0.834	0.750	≥0	≥0%
LogMap	25	2,330	0	0.985	0.587	0.736	≥0	≥0%
Wiktionary	858	7,336	5	0.479	0.899	0.625	≥3,288	≥24.1%
LogMapLt	8	1,747	10	0.993	0.444	0.614	≥0	≥0%
ALOD2Vec	2,809	7,805	457	0.454	0.907	0.605	≥12,787	≥93.6%
ATBox	21	1,318	17	0.986	0.333	0.498	≥0	≥0%